Wintery Knight

…integrating Christian faith and knowledge in the public square

Stephen C. Meyer lectures on intelligent design and the origin of life

A MUST-SEE lecture based on Dr. Stephen C. Meyer’s book “Signature in the Cell“.

You can get an MP3 of the lecture here. (30 MB)

I highly recommend watching the lecture, and looking at the slides. The quality of the video and the content is first class. There is some Q&A (9 minutes) at the end of the lecture.


  • intelligent design is concerned with measuring the information-creating capabilities of natural forces like mutation and selection
  • Darwinists think that random mutations and natural selection can explain the origin and diversification of living systems
  • Darwinian mechanisms are capable of explaining small-scale adaptive changes within types of organisms
  • but there is skepticism, even among naturalists, that Darwinian mechanisms can explain the origin of animal designs
  • even if you concede that Darwinism can account for all of the basic animal body plans, there is still the problem of life’s origin
  • can Darwinian mechanisms explain the origin of the first life? Is there a good naturalistic hypothesis to explain it?
  • there are at least two places in the history of life where new information is needed: origin of life, and Cambrian explosion
  • overview of the structure of DNA and protein synthesis (he has helpful pictures and he uses the snap lock blocks, too)
  • the DNA molecule is composed of a sequence of proteins, and the sequence is carefully selected to have biological function
  • meaningful sequences of things like computer code, English sentences, etc. require an adequate cause
  • it is very hard to arrive at a meaningful sequence of a non-trivial length by randomly picking symbols/letters
  • although any random sequence of letters is improbable, the vast majority of sequences are gibberish/non-compiling code
  • similarly, most random sequences of amino acids are lab-proven (Doug Axe’s work) to be non-functional gibberish
  • the research showing this was conducted at Cambridge University and published in the Journal of Molecular Biology
  • so, random mutation cannot explain the origin of the first living cell
  • however, even natural selection coupled with random mutation cannot explain the first living cell
  • there must already be replication in order for mutation and selection to work, so they can’t explain the first replicator
  • but the origin of life is the origin of the first replicator – there is no replication prior to the first replicator
  • the information in the first replicator cannot be explained by law, such as by chemical bonding affinities
  • the amino acids are attached like magnetic letters on a refrigerator
  • the magnetic force sticks the letters ON the fridge, but they don’t determine the specific sequence of the letters
  • if laws did determine the sequence of letters, then the sequences would be repetitive
  • the three materialist explanations – chance alone, chance and law, law alone – are not adequate to explain the effect
  • the best explanation is that an intelligent cause is responsible for the biological explanation in the first replicator
  • we know that intelligent causes can produce functional sequences of information, e.g. – English, Java code
  • the structure and design of DNA matches up nicely with the design patterns used by software engineers (like WK!)

There are some very good tips in this lecture so that you will be able to explain intelligent design to others in simple ways, using everyday household items and children’s toys to symbolize the amino acids, proteins, sugar phosphate backbones, etc.

Proteins are constructed from a sequence of amino acids:

A sequence of amino acids forming a protein

A sequence of amino acids forming a protein

Proteins sticking onto the double helix structure of DNA:

Some proteins sticking onto the sugar phosphate backbone

Some proteins sticking onto the sugar phosphate backbone

I highly, highly recommend this lecture. You will be delighted and you will learn something.

Here is an article that gives a general overview of how intelligent design challenges. If you want to read something more detailed about the material that he is covering in the lecture above related to the origin of life, there is a pretty good article here.

UPDATE: There is a good breakdown of some of the slides with helpful flow charts here on Uncommon Descent.

Positive arguments for Christian theism

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How likely is it for blind forces to sequence a functional protein by chance?

How likely is it that you could swish together amino acids randomly and come up with a sequence that would fold up into a functional protein?

Evolution News reports on research performed by Doug Axe at Cambridge University, and published in the peer-reviewed Journal of Molecular Biology.


Doug Axe’s research likewise studies genes that it turns out show great evidence of design. Axe studied the sensitivities of protein function to mutations. In these “mutational sensitivity” tests, Dr. Axe mutated certain amino acids in various proteins, or studied the differences between similar proteins, to see how mutations or changes affected their ability to function properly.10 He found that protein function was highly sensitive to mutation, and that proteins are not very tolerant to changes in their amino acid sequences. In other words, when you mutate, tweak, or change these proteins slightly, they stopped working. In one of his papers, he thus concludes that “functional folds require highly extraordinary sequences,” and that functional protein folds “may be as low as 1 in 10^77.”11 The extreme unlikelihood of finding functional proteins has important implications for intelligent design.

Just so you know, those footnotes say this:

[10.] Douglas D. Axe, “Estimating the Prevalence of Protein Sequences Adopting Functional Enzyme Folds,” Journal of Molecular Biology, 1-21 (2004); Douglas D. Axe, “Extreme Functional Sensitivity to Conservative Amino Acid Changes on Enzyme Exteriors,” Journal of Molecular Biology, Vol. 301:585-595 (2000).

[11.] Douglas D. Axe, “Estimating the Prevalence of Protein Sequences Adopting Functional Enzyme Folds,” Journal of Molecular Biology, 1-21 (2004).

And remember, you need a lot more than just 1 protein in order to create even the simplest living system. Can you generate that many proteins in the short time between when the Earth cools and the first living cells appear? Even if we spot the naturalist a prebiotic soup as big as the universe, and try to make sequences as fast as possible, it’s unlikely to generate even one protein in the time before first life appears.

Here’s Doug Axe to explain his research:

If you are building a protein for the FIRST TIME, you have to get it right all at once – not by building up to it gradually using supposed Darwinian mechanisms. That’s because there is no replication before you have the first replicator. The first replicator cannot rely on explanations that require replication to already be in place.

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Stephen C. Meyer debates Peter D. Ward on intelligent design and evolution

The speakers

Stephen C. Meyer is director of the Discovery Institute’s Center for Science and Culture (CSC) and a founder both of the intelligent design movement and of the CSC, intelligent design’s primary intellectual and scientific headquarters. Dr. Meyer is a Cambridge University-trained philosopher of science, the author of peer-reviewed publications in technical, scientific, philosophical and other books and journals. His signal contribution to ID theory is given most fully in Signature in the Cell: DNA and the Evidence for Intelligent Design, published by HarperOne in June 2009.

Graduating from Whitworth College in Spokane, Washington, in 1981 with a degree in physics and earth science, he later became a geophysicist with Atlantic Richfield Company (ARCO) in Dallas, Texas. From 1981 to 1985, he worked for ARCO in digital signal processing and seismic survey interpretation. As a Rotary International Scholar, he received his training in the history and philosophy of science at Cambridge University, earning a PhD in 1991. His thesis offered a methodological interpretation of origin-of-life research.

Peter D. Ward, Ph.D., is a paleontologist and professor in the Departments of Geology and Biology at the University of Washington in Seattle. He also serves as an adjunct professor of zoology and astronomy. His research specialties include the Cretaceous–Tertiary extinction event and mass extinctions generally. His books include the best-selling “Rare Earth: Why Complex Life Is Uncommon in the Universe” (co-author Donald Brownlee, 2000), “Under a Green Sky: Global Warming, the Mass Extinctions of the Past, and What They Can Tell Us About Our Future” (2007), and “The Medea Hypothesis: Is Life on Earth Ultimately Self-Destructive?” (2009).

The debate

Here’s the video of the debate:

The debate itself starts at around 8:19, after all the moderators have spoken.

The debate is focused on disagreements about scientific evidence.

Even though Peter Ward is an atheist, he has co-written a fabulous book that I own and have read called “Rare Earth: Why Complex Life is Uncommon in the Universe“. I really recommend getting this book, as it is a great book by two non-theists on the habitability argument. It’s sort of a secular precursor to Jay Richards’ and Guillermo Gonzalez’s “The Privileged Planet: How Our Place in the Cosmos is Designed for Discovery“. The habitability argument is a really neglected argument, but it’s a good one.

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Study: the early Earth’s atmosphere contained oxygen

Here’s a paper published in the prestigious peer-reviewed science journal Nature, entitled “The oxidation state of Hadean magmas and implications for early Earth’s atmosphere”. This paper is significant because it undermines naturalistic scenarios for the origin of life.

Evolution News explains what the paper is about.


A recent Nature publication reports a new technique for measuring the oxygen levels in Earth’s atmosphere some 4.4 billion years ago. The authors found that by studying cerium oxidation states in zircon, a compound formed from volcanic magma, they could ascertain the oxidation levels in the early earth. Their findings suggest that the early Earth’s oxygen levels were very close to current levels.

[...]Miller and Urey conducted experiments to show that under certain atmospheric conditions and with the right kind of electrical charge, several amino acids could form from inorganic compounds such as methane, ammonia, and water. Several experiments have been done using various inorganic starting materials, all yielding a few amino acids; however, one key aspect of all of these experiments was the lack of oxygen.

If the atmosphere has oxygen (or other oxidants) in it, then it is an oxidizing atmosphere. If the atmosphere lacks oxygen, then it is either inert or a reducing atmosphere. Think of a metal that has been left outside, maybe a piece of iron. That metal will eventually rust. Rusting is the result of the metal being oxidized. With organic reactions, such as the ones that produce amino acids, it is very important that no oxygen be present, or it will quench the reaction. Scientists, therefore, concluded that the early Earth must have been a reducing environment when life first formed (or the building blocks of life first formed) because that was the best environment for producing amino acids. The atmosphere eventually accumulated oxygen, but life did not form in an oxidative environment.

The problem with this hypothesis is that it is based on the assumption that organic life must have formed from inorganic materials. That is why the early Earth must have been a reducing atmosphere. Research has been accumulating for more than thirty years, however, suggesting that the early Earth likely did have oxygen present.

[...]Their findings not only showed that oxygen was present in the early Earth atmosphere, something that has been shown in other studies, but that oxygen was present as early as 4.4 billion years ago. This takes the window of time available for life to have begun, by an origin-of-life scenario like the RNA-first world, and reduces it to an incredibly short amount of time. Several factors need to coincide in order for nucleotides or amino acids to form from purely naturalistic circumstances (chance and chemistry). The specific conditions required already made purely naturalist origin-of-life scenarios highly unlikely. Drastically reducing the amount of time available, adding that to the other conditions needing to be fulfilled, makes the RNA world hypothesis or a Miller-Urey-like synthesis of amino acids simply impossible.

So here’s where we stand. If you are a materialist, then you need a reducing environment on the early Earth in order to get organic building blocks (amino acids) from inorganic materials. However, the production of these organic building blocks (amino acids) requires that the early Earth atmosphere be oxygen-free. And the problem with this new research, which confirms previous research, is that the early Earth contained huge amounts of oxygen – the same amount of oxygen as we have today. This is lethal to naturalistic scenarios for creating the building blocks of life on the Earth’s surface.

Other problems

If you would like to read a helpful overview of the problems with a naturalistic scenario for the origin of life, check out this article by Casey Luskin.


The “origin of life” (OOL) is best described as the chemical and physical processes that brought into existence the first self-replicating molecule. It differs from the “evolution of life” because Darwinian evolution employs mutation and natural selection to change organisms, which requires reproduction. Since there was no reproduction before the first life, no “mutation – selection” mechanism was operating to build complexity. Hence, OOL theories cannot rely upon natural selection to increase complexity and must create the first life using only the laws of chemistry and physics.

There are so many problems with purely natural explanations for the chemical origin of life on earth that many scientists have already abandoned all hopes that life had a natural origin on earth. Skeptical scientists include Francis Crick (solved the 3-dimensional structure of DNA) and Fred Hoyle (famous British cosmologist and mathematician), who, in an attempt to retain their atheistic worldviews, then propose outrageously untestable cosmological models or easily falsifiable extra-terrestrial-origin-of-life / panspermia scenarios which still do not account for the natural origin of life. So drastic is the evidence that Scientific American editor John Horgan wrote, “[i]f I were a creationist, I would cease attacking the theory of evolution … and focus instead on the origin of life. This is by far the weakest strut of the chassis of modern biology.”3

The article goes over the standard problems with naturalistic scenarios of the origin of life: wrong atmosphere, harmful UV radiation, interfering cross-reactions, oxygen levels, meteorite impacts, chirality, etc.

Most people who are talking about intelligent design at the origin of life talk about the information problem – how do you get the amino acids to form proteins and how do you get nucleotide bases to code for amino acids? But the starting point for solving the sequencing problem is the construction of the amino acids – there has to be a plausible naturalistic scenario to form them.

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Michael Ruse debates Stephen C. Meyer on intelligent design and evolution on NPR

Details: (from NPR web site)

About one third of Americans believe in intelligent design, according to a recent Gallup poll. That’s the idea that humans evolved over time from lesser life forms – with the process guided by God. It’s added a new dimension to the old debate over where humans come from and raised serious concern in the scientific world about mixing faith with science.

  • Stephen C. Meyer, author of Darwin’s Doubt: The Explosive Origin of Animal Life and the Case for Intelligent Design
  • Michael Ruse, Director of the History and Philosophy of Science Program at Florida State University

The MP3 file is here. (28 minutes)

The following summary is rated S for Slightly Snarky. Reader discretion is advised.


  • Moderator: (to Meyer) define creationism, evolution, and intelligent design
  • Meyer: creationism is based on an interpretation of the Bible
  • Meyer: evolution is an unguided process of mutation and selection that produces organisms
  • Meyer: intelligent design is the idea that the best explanation for certain features of life
  • Moderator: (to Ruse) Where do you disagree?
  • Ruse: Intelligent design is similar to creationism, but I won’t say how exactly
  • Meyer: ID is a good explanation for the sudden origin of animal body plans in the Cambrian era
  • Moderator: (to Meyer) Is the designer God? Is the designer the Christian God?
  • Meyer: No, ID theory is an inference that is rooted in scientific evidence, not in a religious text
  • Meyer: ID can be inferred from the origin of biological information and from molecular machines
  • Moderator: (to Ruse) Where do you disagree?
  • Ruse: Meyer is disingenuous because ID requires the designer to be God
  • Meyer: The biological evidence for intelligent design by itself does not implicate God
  • Meyer: The fine-tuning of the cosmos is intelligent design in physics, and that *would* require God
  • Moderator: (to Meyer) Explain what the Cambrian explosion is
  • Meyer: sudden origin of 36 body plans in 10 million years 530 million years ago
  • Moderator: So you think that 36 body plans in 10 million years is too sudden for Darwinian mechanisms to produce?
  • Meyer: Yes, for two reasons. One, there are no precursors prior to the start of the explosion in complexity
  • Meyer: And two, the complexity of animal life includes code, circuitry, hierarchies – best explained by a designer
  • Moderator: (to Ruse) Is it a problem for you?
  • Ruse: There is no peer-reviewed paper that denies that the Ediacaran fauna are precursors to the Cambrian animals
  • Ruse: There is no peer-reviewed paper that denies that microfossils are precursors to the Cambrian animals
  • Ruse: There is no peer-reviewed paper that denies that animal complexity goes from simple to complex in the fossil record
  • Ruse: There is no peer-reviewed paper that shows that the Cambrian explosion took place over a few million years
  • Ruse: There is no peer-reviewed paper that shows that there were complex organ types at the start of the Cambrian explosion
  • Ruse: There is no peer-reviewed paper that denies that we already have a materialist explanation for the Cambrian explosion
  • Ruse: everything is solved! nothing to see here! (folds arms and beams) I trust that my unsupported assertions have relieved your doubts, yes?
  • Moderator: Is intelligent design undermined by more recent science?
  • Meyer: no, there is an absence of precursor fossils in the period before the Cambrian explosion
  • Meyer: there are other things that make the problem even worse for naturalism, like information from epigenetics
  • Moderator: (to Ruse) Answer that
  • Ruse: He is just pulling out passages out of context because he is a creationist!
  • Moderator: The leftist New Yorker reviewer Gareth Cook says that the Cambrian explosion took tens of millions of years
  • Meyer: Actually, the peer-reviewed science is clear that the standard date is at most 10 million nears
  • Moderator: (to Ruse) Deny the mainstream date
  • Ruse: Well, Prothero says no! Ho ho ho! (folds arms) He just says it. No it’s not published in peer-reviewed research
  • Ruse: We know so much more than Darwin did, how could the progress of science disprove my materialist pre-supposition? It’s unpossible!
  • Moderator: (to Meyer) Isn’t ID pseudo-science?
  • Meyer: If we limit ourselves to materialist explanations only, then we cannot infer intelligence when we see artifacts like the Rosetta Stone
  • Meyer: wind and erosion is not an adequate explanation for certain systems – systems that are rich in information
  • Meyer: the best explanation is the explanation that relies on known causes – we know that intelligence produces information
  • Moderator: (to Meyer) so the intelligence is the best explanation of systems that have information?
  • Meyer: yes, think about software code – the best explanation of new computer instructions is an intelligence
  • Meyer: we have uniform and repeated experience of intelligence bringing new information into being, and new animals need new information
  • Moderator: (to Ruse) must science only work with natural explanations?
  • Ruse: intelligent design is religion! Ho ho ho ho! (folds arms)
  • Ruse: there is no a priori way of ruling out supernatural causes in order to explain nature
  • Ruse: We don’t need to introduce supernatural causes to explain information in living systems or in software code
  • Ruse: Steve is asking me to explain the Cambrian explosion, but why does he want me to explain that?
  • Ruse: How did anything start to fly? How did whales come? There, those questions explain the Cambrian explosion naturalistically
  • Ruse: Steve’s answer to explain new information is to bring in miracles, like when he said that new computer code requires God
  • Ruse: inferring intelligence as an explanation for information like the computer code is religion! God! Creationism! Prayer in schools!
  • Ruse: we have to keep looking for naturalistic explanations for the Big Bang, the DNA, the fine-tuning, the Cambrian fossils, etc.
  • Ruse: we are never justified in inferring an intelligence to explain information, because that would deny my religion of materialism
  • Moderator: (to Ruse) what are the requirements for a theory to be scientific?
  • Ruse: any explanation has to be naturalistic, because I am an atheist and that’s my religion, and we can’t go against my religion
  • Ruse: it’s “really stupid” to infer God as the explanation of the creation of the entire physical universe or the cosmic fine-tuning
  • Moderator: (to Meyer) why is intelligent design so popular when we have court cases saying it is not science?
  • Meyer: the Discovery Institute does not have an agenda to teach intelligent design in public schools
  • Meyer: intelligent design is about inferring intelligence as a causal explanation for information in living systems, and elsewhere
  • Moderator: (to Ruse) are evolutionists unwilling to entertain the possibility of intelligence being the best explanation?
  • Ruse: scientists have to make sure that that all their explanations don’t go outside of the materialist reservation
  • Ruse: intelligent design is evangelical Christianity dressed up to look like science, the Dover judge said so
  • Ruse: Meyer is disingenuous! Ho ho ho ho ho! (folds arms contentedly)
  • Meyer: first, judges don’t decide science, evidence decides science
  • Meyer: the Dover people made a mistake by trying to go to the courts to get things into the schools
  • Meyer: intelligent design is about research, writing books and papers based on what we learn from science
  • Moderator: (to Ruse) is intelligent design dangerous?
  • Ruse: yes, intelligent design is about politics, it’s not about cosmic fine-tuning, origin of life, molecular machines or Cambrian explosion
  • Ruse: intelligent design is about abstinence, prayer in schools, burdening women with unwanted babies and male-female marriage
  • Ruse: my reason for opposing ID is the socially conservative agenda which emerges from protein folding probability calculations
  • Ruse: I don’t want to be drafted to fight in Vietnam, I don’t want them to take away my drugs, etc. so that’s why I believe Darwinism
  • Moderator: (to Meyer) why do you want to take abortion away, you meany?
  • Meyer: actually, intelligent design is about science, and in any case National Review gave my book a bad review
  • Moderator: (to Ruse) are science and religion in conflict?
  • Ruse: well religion can just abstain from making any claims about the physical world, and just stick to subjective nonsense – that’s fair
  • Moderator: (to Meyer) isn’t all opposition to evolution rooted in fundamentalist religion?
  • Meyer: you can believe in Darwinism and be a theist, but the real reason for doubting Darwinism is the scientific evidence, not religion

Tell me how you think Dr. Meyer did in the comments. I think that Ruse is a Darwinist because he views it as a way to push people away from the conservative morality and politics. But he’s a nice guy, and I appreciate him debating the issue. Things are tough right now for his side.

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