Wintery Knight

…integrating Christian faith and knowledge in the public square

Study confirms that predictions about junk DNA by materialists are false

First, let’s see what Darwinian evolutionists predict about junk DNA, before we look at what the experiments show.

Here’s biologist John Timmer to explain the orthodox Darwinian view of DNA from 2007:

Personally, I fall into the “it’s all junk” end of the spectrum. If almost all of these sequences are not conserved by evolution, and we haven’t found a function for any of them yet, it’s hard to see how the “none of it’s junk” view can be maintained. There’s also an absence of support for the intervening view, again because of a lack of evidence for actual utility. The genomes of closely related species have revealed very few genes added from non-coding DNA, and all of the structural RNA we’ve found has very specific sequence requirements. The all-junk view, in contrast, is consistent with current data.

Got that? According to Darwinists, DNA is almost entirely junk – this is what is consistent with the view that creatures have evolved through a process of random mutation and selection. The estimates that I’ve seen from evolutionary biologists range from 95% to 99% junk. Now let’s compare the religion with science, and separate mythology from reality.

Now let’s compare that with intelligent design theorist William Dembski’s view of “junk” DNA, from 1998:

Even if we have a reliable criterion for detecting design, and even if that criterion tells us that biological systems are designed, it seems that determining a biological system to be designed is akin to shrugging our shoulders and saying God did it. The fear is that admitting design as an explanation will stifle scientific inquiry, that scientists will stop investigating difficult problems because they have a sufficient explanation already.

But design is not a science stopper. Indeed, design can foster inquiry where traditional evolutionary approaches obstruct it. Consider the term “junk DNA.” Implicit in this term is the view that because the genome of an organism has been cobbled together through a long, undirected evolutionary process, the genome is a patchwork of which only limited portions are essential to the organism. Thus on an evolutionary view we expect a lot of useless DNA. If, on the other hand, organisms are designed, we expect DNA, as much as possible, to exhibit function. And indeed, the most recent findings suggest that designating DNA as “junk” merely cloaks our current lack of knowledge about function… Design encourages scientists to look for function where evolution discourages it.

Now let’s look at the experimental evidence and see whose prediction was proven right by the progress of science.

Science Daily reports on a recent study that confirms the previous study that falsified Darwinian predictions about junk DNA.

Excerpt:

Researchers from the Gene and Stem Cell Therapy Program at Sydney’s Centenary Institute have confirmed that, far from being “junk,” the 97 per cent of human DNA that does not encode instructions for making proteins can play a significant role in controlling cell development.

[...]Using the latest gene sequencing techniques and sophisticated computer analysis, a research group led by Professor John Rasko AO and including Centenary’s Head of Bioinformatics, Dr William Ritchie, has shown how particular white blood cells use non-coding DNA to regulate the activity of a group of genes that determines their shape and function. The work is published today in the scientific journalCell.

“This discovery, involving what was previously referred to as “junk,” opens up a new level of gene expression control that could also play a role in the development of many other tissue types,” Rasko says. “Our observations were quite surprising and they open entirely new avenues for potential treatments in diverse diseases including cancers and leukemias.”

Now, this is yet another falsification of Darwinism, to go with the other papers that I keep posting about new research that falsifies Darwinism. How many papers do we need to falsify Darwinism? I think if you are in an argument over Darwinism, and you produce these articles, then you win, so long as the other person cannot produce anything. It’s also a good idea to couple these pieces of evidence with a positive case for intelligent causes operating during the origin of life and the Cambrian explosion.

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Is there a smooth pathway from micro-evolution to macro-evolution?

From Luke Nix who blogs at Faithful Thinkers.

Excerpt:

Macroevolutionary changes are a lot of microevolutionary changes, but they are in a specific series that follow a specific pathway. The missing premise in this argument is that the pathway from ancestor to claimed offspring (many generations down the road) is clear of obstacles.

In his book, “The Edge of Evolution” Michael Behe shows that scientists have observed such an obstacle in the lab. The obstacle was not time, it is in the genetic pathway that must be traversed if macroevolutionary changes are to take place in reality. Since an obstacle has been observed, we now have a false premise in the argument. Since there is a false premise, the argument fails. There is a difference between micro- and macro-evolutionary changes. A lot of microevolutionary changes are necessary for macroevolution, but they are not sufficient. The other sufficient condition (a clear genetic pathway) still has yet to be met. Since both sufficient conditions for macroevolution have not been met, it has not been demonstrated. And since changes over time has been demonstrated, there is a need to distinguish between the two. To prevent confusion about what we know to be true and what we don’t, this distinction must be made.

There is only one way that this can be overcome by the naturalist: find a pathway that would be clear by default in nature. Notice that I have added one more piece to the missing premise above: “…clear by default in nature“. I have to add that last qualification because as scientists are looking for a way to overcome this obstacle, they are introducing their own intelligence- fine-tuning the process, then “allowing nature to take its course”. Their conclusion of naturalistic macroevolution will depend on a premise that is founded on intelligence. That would undermine the whole argument for naturalistic (macro)evolution.

This is one of the ways to show that evolution is true – by showing a pathway to macro-evolutionary change in the lab. If people expect me to believe in the grandiose claims of fully naturalistic evolution through a stepwise process, then why can’t I see the pathway myself? If you make the claim that it happened, then I want to see the evidence for the claim.

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New study confirms that predictions about junk DNA by Darwinian naturalists are false

First, let’s see what Darwinian evolutionists predict about junk DNA, before we look at what the experiments show.

Here’s biologist John Timmer to explain the orthodox Darwinian view of DNA from 2007:

Personally, I fall into the “it’s all junk” end of the spectrum. If almost all of these sequences are not conserved by evolution, and we haven’t found a function for any of them yet, it’s hard to see how the “none of it’s junk” view can be maintained. There’s also an absence of support for the intervening view, again because of a lack of evidence for actual utility. The genomes of closely related species have revealed very few genes added from non-coding DNA, and all of the structural RNA we’ve found has very specific sequence requirements. The all-junk view, in contrast, is consistent with current data.

Got that? According to Darwinists, DNA is almost entirely junk – this is what is consistent with the view that creatures have evolved through a process of random mutation and selection. The estimates that I’ve seen from evolutionary biologists range from 95% to 99% junk. Now let’s compare the religion with science, and separate mythology from reality.

Now let’s compare that with intelligent design theorist William Dembski’s view of “junk” DNA, from 1998:

Even if we have a reliable criterion for detecting design, and even if that criterion tells us that biological systems are designed, it seems that determining a biological system to be designed is akin to shrugging our shoulders and saying God did it. The fear is that admitting design as an explanation will stifle scientific inquiry, that scientists will stop investigating difficult problems because they have a sufficient explanation already.

But design is not a science stopper. Indeed, design can foster inquiry where traditional evolutionary approaches obstruct it. Consider the term “junk DNA.” Implicit in this term is the view that because the genome of an organism has been cobbled together through a long, undirected evolutionary process, the genome is a patchwork of which only limited portions are essential to the organism. Thus on an evolutionary view we expect a lot of useless DNA. If, on the other hand, organisms are designed, we expect DNA, as much as possible, to exhibit function. And indeed, the most recent findings suggest that designating DNA as “junk” merely cloaks our current lack of knowledge about function… Design encourages scientists to look for function where evolution discourages it.

Now let’s look at the experimental evidence and see whose prediction was proven right by the progress of science.

Science Daily reports on a new study that confirms the previous study that falsified Darwinian predictions about junk DNA.

Excerpt:

Researchers from the Gene and Stem Cell Therapy Program at Sydney’s Centenary Institute have confirmed that, far from being “junk,” the 97 per cent of human DNA that does not encode instructions for making proteins can play a significant role in controlling cell development.

[...]Using the latest gene sequencing techniques and sophisticated computer analysis, a research group led by Professor John Rasko AO and including Centenary’s Head of Bioinformatics, Dr William Ritchie, has shown how particular white blood cells use non-coding DNA to regulate the activity of a group of genes that determines their shape and function. The work is published today in the scientific journalCell.

“This discovery, involving what was previously referred to as “junk,” opens up a new level of gene expression control that could also play a role in the development of many other tissue types,” Rasko says. “Our observations were quite surprising and they open entirely new avenues for potential treatments in diverse diseases including cancers and leukemias.”

Now, this is yet another falsification of Darwinism, to go with the other papers that I keep posting about new research that falsifies Darwinism. How many papers do we need to falsify Darwinism? Or maybe belief in Darwinism is like belief in naturalism: just a philosophical presupposition that is not accountable to the evidence at all.

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Is it better to form beliefs based on evidence or based on consensus?

Stuart Schneiderman linked to this Wall Street Journal by Matt Ridley.

Take a look at this:

Last week a friend chided me for not agreeing with the scientific consensus that climate change is likely to be dangerous. I responded that, according to polls, the “consensus” about climate change only extends to the propositions that it has been happening and is partly man-made, both of which I readily agree with. Forecasts show huge uncertainty.

Besides, science does not respect consensus. There was once widespread agreement about phlogiston (a nonexistent element said to be a crucial part of combustion), eugenics, the impossibility of continental drift, the idea that genes were made of protein (not DNA) and stomach ulcers were caused by stress, and so forth—all of which proved false. Science, Richard Feyman once said, is “the belief in the ignorance of experts.”

My friend objected that I seemed to follow the herd on matters like the reality of evolution and the safety of genetically modified crops, so why not on climate change? Ah, said I, but I don’t. I agree with the majority view on evolution, not because it is a majority view but because I have looked at evidence. It’s the data that convince me, not the existence of a consensus.

My friend said that I could not possibly have had time to check all the evidence for and against evolution, so I must be taking others’ words for it. No, I said, I take on trust others’ word that their facts are correct, but I judge their interpretations myself, with no thought as to how popular they are. (Much as I admire Charles Darwin, I get fidgety when his fans start implying he is infallible. If I want infallibility, I will join the Catholic Church.)

And that is where the problem lies with climate change. A decade ago, I was persuaded by two pieces of data to drop my skepticism and accept that dangerous climate change was likely. The first, based on the Vostok ice core, was a graph showing carbon dioxide and temperature varying in lock step over the last half million years. The second, the famous “hockey stick” graph, showed recent temperatures shooting up faster and higher than at any time in the past millennium.

Within a few years, however, I discovered that the first of these graphs told the opposite story from what I had inferred. In the ice cores, it is now clear that temperature drives changes in the level of carbon dioxide, not vice versa.

As for the “hockey stick” graph, it was effectively critiqued by Steven McIntyre, a Canadian businessman with a mathematical interest in climatology. He showed that the graph depended heavily on unreliable data, especially samples of tree rings from bristlecone pine trees, the growth patterns of which were often not responding to temperature at all. It also depended on a type of statistical filter that overweighted any samples showing sharp rises in the 20th century.

I followed the story after that and was not persuaded by those defending the various hockey-stick graphs. They brought in a lake-sediment sample from Finland, which had to be turned upside down to show a temperature spike in the 20th century; they added a sample of larch trees from Siberia that turned out to be affected by one tree that had grown faster in recent decades, perhaps because its neighbor had died. Just last week, the Siberian larch data were finally corrected by the University of East Anglia to remove all signs of hockey-stick upticks, quietly conceding that Mr. McIntyre was right about that, too.

So, yes, it is the evidence that persuades me whether a theory is right or wrong, and no, I could not care less what the “consensus” says.

I think that one of the most troubling things about college students today is that they are so much under the influence of their professors that they regularly just parrot whatever their professors say in order to pass their classes. They can’t afford to ask questions and disagree – they’ve already paid their money, and their job is to agree with the professors in order to pass. This is especially true with secular leftist professors who are often woefully incapable of respecting views other than their own. The ivory tower is not the best place for having one’s views tested by reality, as Thomas Sowell has argued. This is especially true outside of the fields of engineering, math, science and technology. So, young people tend to come out of university parroting the view of their professors, who often don’t know how the real world works at all. The right thing to do to fix this problem is for universities to promote a diversity of views. But that’s not likely to happen in universities that are dominated by progressives. Non-progressive views are not just wrong, but evil. Rather than be viewed as evil by professors and peers for the crime of thinking critically, most students prefer to stick with the consensus views, whether they are defensible or not.

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New study: function found for beta-globin pseudogene that was labeled “junk” during Dover trial

Casey Luskin tells us about a new study in Evolution News.

Excerpt:

A new paper in Genome Biology and Evolution argues that the famous beta-globin pseudogene is functional. Why is this pseudogene famous?

Well, it’s been Exhibit A — literally, offered as evidence in a court case — for critics of intelligent design who argue that our genome is full of useless, functionless junk, and therefore can’t be a product of design. Near the beginning of his testimony on the very first day of the 2005 Kitzmiller v. Dover trial, Brown University biology professor Kenneth Miller testified to the court that the beta-globin pseudogene is “broken, and it has a series of molecular errors that render the gene non-functional.” (Day 1 AM, p. 79.) He further told the court:

And the fact that all three of these species have matching mistakes leads us to just one conclusion, and that’s the same conclusion that Charles Darwin predicted almost a century and a half ago, and that is that these three species share a common ancestor. Matching mistakes are evidence of common ancestry. (Day 1 AM, p. 81)

In his 2008 book Only a Theory, Miller is even more explicit in asserting that this pseudogene refutes intelligent design. He writes that “A detailed analysis of the beta-globin pseudogene shows a series of mutations have rendered it nonfunctional” (p. 102). In Miller’s view, that takes care of ID:

The gorilla and chimpanzee pseudogenes have exactly the same set of molecular errors [in their beta-globin pseudogene] … There’s no escaping the implication of these matching mistakes, and there’s no point in arguing that six identical mistakes could have turned up independently in three unrelated species. The only sensible interpretation is that the original errors developed at random in a single common ancestor of these three species. In a court of genetic copyright law, any motion that a designer could claim originality for the human genome would be tossed out in a flash. (pp. 102-103)

Now a new paper in Genome Biology and Evolution, “Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation, argues that the beta-globin pseudogene is not broken, but in fact performs an important function in regulating gene expression.

Remember, Darwinists are still reeling from the ENCODE study that found that the non-coding DNA that they said was 100% junk was actually 80% functional. The trouble is that they are always letting their philosophy of naturalism get in the way of their science. They assume that nature is all there is. They assumed that everything is not designed. Then they are quick to say that things that aren’t junk are junk, in order to confirm their assumption. Problems occur later when good science comes along and proves their philosophical assumption of naturalism wrong. Do they then give up the philosophical assumption? Heck no – that’s their religion! But they ought to give it up if they were honest, and stick with the science instead. Too much bad religion among the Darwinists – that’s the problem.

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