Casey Luskin and Stephen C. Meyer discuss the design inference

This episode of ID the Future is 17 minutes long. It’s the third in a series – here are parts one and two.

Details:

On this episode of ID the Future, Casey Luskin and Stephen Meyer finish up their talk with a discussion of why intelligent design presents the best explanation for the Cambrian explosion.

Special limited time offer: Save 43% and get 4 free digital books when you pre-order Darwin’s Doubt.

You can grab the MP3 here.

Topics:

•  What sort of reasoning did Darwin use in The Origin of Species?
• Can this method of “inference to the best explanation” be applied to the Cambrian explosion
• The importance of appealing to causes that we have experienced ourselves
• Example: explaining from an effect (volcanic ash) to a cause that his adequate (volcanic eruption)
• We have experience of how volcanoes cause the ash, so we should infer based on what we know
• In the case where the effect is information in biology, we see that naturalistic mechanisms are inadequate
• But we know from our own experience that intelligent agents can generate information
• Many people think that science must confine itself to materialistic explanations
• If so, then it is possible miss out on the true explanation by ruling it out before looking at evidence

If you haven’t yet read Meyer’s first book, “Signature in the Cell”, you should probably grab that one. It’s the best book on intelligent design that’s out right now. It talks about the origin of the first living cell, surveying all naturalistic explanations for it, and concluding that the best explanation – the one most consistent with what we know now – is intelligent design.

Filed under: Podcasts, Biological Information, Body Plan, Charles Darwin, Darwinism, Epigenetic, Evolution, Genetic, Information, Mutation, Origin of Life, Protein, Selection, Specified Complexity, Stephen C. Meyer

Casey Luskin and Stephen C. Meyer discuss information outside the genome

This episode of ID the Future is 20 minutes long and it’s a follow up to a previous podcast I posted.

Details:

On this episode of ID the Future, hear the second part of Casey Luskin’s interview with Dr. Stephen C. Meyer, author of the forthcoming book Darwin’s Doubt: The Explosive Origin of Animal Life and the Case for Intelligent Design. Dr. Meyer discusses how the origin of information in the Cambrian explosion poses a problem for evolutionary biology.

Special limited time offer: Save 43% and get 4 free digital books when you pre-order Darwin’s Doubt.

You can grab the MP3 here.

Topics:

• Last time, they discussed how the sudden origin of animal body plans requires an infusion of new information
• Also, the sudden origin of animal forms is inexplicable naturalistically, because there are no transitional forms
• New body plans require new genetic information
• The Cambrian explosion involve a sudden increase of body plans, which means a sudden increase of information
• For example, a new body plan requires dozens of new cell types
• Each cell type will be composed of new proteins and enzymes
• Proteins are composed of functional sequences of amino acids – genetic information
• Can the neo-Darwinian mechanisms generate new functional sequences?
• The problem with making functional sequences by chance: Product Rule
• When calculating probabilities of forming a functional sequence, you multiply to calculate probabilities
• A bike lock with 4 dials and 10 possibilities has 10 x 10 x 10 x 10 = 10,000 possibilities
• Each sequence is equally likely to get by random guesses
• But it’s far more likely that any random attempt will NOT work
• Getting one or two settings right has no value to opening the lock, and will not be saved for later attempts
• There is no credit for partial success: you have to get the whole combination right the first time
• In addition, there are other sources of information other than DNA that are required for new body plans
  
• For example, there is information in cell membranes, cytoskeletons, etc. which is also needed
• Neo-Darwinism can only work on mutating genes – even in the best case it would just give you new proteins
• Neo-Darwinism cannot add information in non-genome areas, which are required for new animal forms
• The information in these non-genome areas are required to arrange the proteins to make new body pans
• Genetic inofrmation = information in the genome, Epigenetic information = information outside the genome
• This problem of information outside the genome is called “the problem of the origin of form”

So those last few points are, I think, a sneak peek into the contents of the new “Darwin’s Doubt” book.

If you haven’t yet read Meyer’s first book, “Signature in the Cell”, you should probably grab that one. It’s the best book on intelligent design that’s out right now. It talks about the origin of the first living cell, surveying all naturalistic explanations for it, and concluding that the best explanation – the one most consistent with what we know now – is intelligent design.

Filed under: Podcasts, Biological Information, Body Plan, Charles Darwin, Darwinism, Epigenetic, Evolution, Genetic, Information, Mutation, Origin of Life, Protein, Selection, Specified Complexity, Stephen C. Meyer

Doug Axe explains the chances of getting a functional protein by chance

I’ve talked about Doug Axe before when I described how to calculate the odds of getting functional proteins by chance.

Let’s calculate the odds of building a protein composed of a functional chain of 100 amino acids, by chance. (Think of a meaningful English sentence built with 100 scrabble letters, held together with glue)

Sub-problems:

• BONDING: You need 99 peptide bonds between the 100 amino acids. The odds of getting a peptide bond is 50%. The probability of building a chain of one hundred amino acids in which all linkages involve peptide bonds is roughly (1/2)^99 or 1 chance in 10^30.
• CHIRALITY: You need 100 left-handed amino acids. The odds of getting a left-handed amino acid is 50%. The probability of attaining at random only L–amino acids in a hypothetical peptide chain one hundred amino acids long is (1/2)^100 or again roughly 1 chance in 10^30.
• SEQUENCE: You need to choose the correct amino acid for each of the 100 links. The odds of getting the right one are 1 in 20. Even if you allow for some variation, the odds of getting a functional sequence is (1/20)^100 or 1 in 10^65.

The final probability of getting a functional protein composed of 100 amino acids is 1 in 10^125. Even if you fill the universe with pre-biotic soup, and react amino acids at Planck time (very fast!) for 14 billion years, you are probably not going to get even 1 such protein. And you need at least 100 of them for minimal life functions, plus DNA and RNA.

Research performed by Doug Axe at Cambridge University, and published in the peer-reviewed Journal of Molecular Biology, has shown that the number of functional amino acid sequences is tiny:

Doug Axe’s research likewise studies genes that it turns out show great evidence of design. Axe studied the sensitivities of protein function to mutations. In these “mutational sensitivity” tests, Dr. Axe mutated certain amino acids in various proteins, or studied the differences between similar proteins, to see how mutations or changes affected their ability to function properly. He found that protein function was highly sensitive to mutation, and that proteins are not very tolerant to changes in their amino acid sequences. In other words, when you mutate, tweak, or change these proteins slightly, they stopped working. In one of his papers, he thus concludes that “functional folds require highly extraordinary sequences,” and that functional protein folds “may be as low as 1 in 10^77.”

The problem of forming DNA by sequencing nucleotides faces similar difficulties. And remember, mutation and selection cannot explain the origin of the first sequence, because mutation and selection require replication, which does not exist until that first living cell is already in place.

But you can’t show that to your friends, you need to send them a video. And I have a video!

A video of Doug Axe explaining the calculation

Here’s a clip from Illustra Media’s new ID DVD “Darwin’s Dilemma”, which features Doug Axe and Stephen Meyer (both with Ph.Ds from Cambridge University).

I hope you all read Brian Auten’s review of Darwin’s Dilemma! It was awesome.

Related DVDs

Illustra also made two other great DVDs on intelligent design. The first two DVDs “Unlocking the Mystery of Life” and “The Privileged Planet” are must-buys, but you can watch them on youtube if you want, for free.

Here are the 2 playlists:

• Unlocking the Mystery of Life (12 videos in a playlist)
• The Privileged Planet (12 videos in a playlist)

I also recommend Coldwater Media’s “Icons of Evolution”. All three of these are on sale from Amazon.com.

Related posts

• The origin of the universe from nothing
• The fine-tuning of the cosmological constants to permit life
• The fine-tuning of the galaxy, solar system, and planet to permit life
• Origin of the building blocks in the simplest replicating cell
• Origin of biological information in the simplest replicating cell
• Sudden origins of all major body plans in the Cambrian explosion
• Irreducible complexity in molecular machines
• The limits on what natural selection and random mutation can do
• Peer-reviewed paper says there is no atheistic explanation for the Cambrian explosion
• Does the Cambrian explosion disprove Darwinian evolution?

Filed under: Polemics, Aliens, Amino Acid, Ammonia, Atmosphere, Blind, Block, Boiling, Building, Carbon, Cell, Chemical, Chirality, Compound, Credulity, Crick, Dawkins, Dioxide, Discovery, DNA, Early, Earth, Evidence, Evolution, Extinction, Faith, Flying Spaghetti Monster, Hydrogen, Kenyon, Life, Living, Materialism, Meteorite, Methane, Molecular, Naturalism, Noodly Appendage, OOL, Oparin-Haldane, Origin, Oxydizing, Oxygen, Ozone, Primordial Soup, Product, Progress, Protein, Radiation, Reactant, Reaction, Reason, Reducing, Science, Synthesize, Tar, Thaxton, Ultra-Violet, Ultraviolet, UV, Vapor, Water, Watson

What is intelligent design? Dr. Stephen C. Meyer explains the theory

A MUST-SEE lecture based on Dr. Stephen C. Meyer’s book “Signature in the Cell“.

You can get an MP3 of the lecture here. (30 MB)

I highly recommend watching the lecture, and looking at the slides. The quality of the video and the content is first class. There is some Q&A (9 minutes) at the end of the lecture.

Topics:

• intelligent design is concerned with measuring the information-creating capabilities of natural forces like mutation and selection
• Darwinists think that random mutations and natural selection can explain the origin and diversification of living systems
• Darwinian mechanisms are capable of explaining small-scale adaptive changes within types of organisms
• but there is skepticism, even among naturalists, that Darwinian mechanisms can explain the origin of animal designs
• even if you concede that Darwinism can account for all of the basic animal body plans, there is still the problem of life’s origin
• can Darwinian mechanisms explain the origin of the first life? Is there a good naturalistic hypothesis to explain it?
• there are at least two places in the history of life where new information is needed: origin of life, and Cambrian explosion
• overview of the structure of DNA and protein synthesis (he has helpful pictures and he uses the snap lock blocks, too)
• the DNA molecule is composed of a sequence of proteins, and the sequence is carefully selected to have biological function
• meaningful sequences of things like computer code, English sentences, etc. require an adequate cause
• it is very hard to arrive at a meaningful sequence of a non-trivial length by randomly picking symbols/letters
• although any random sequence of letters is improbable, the vast majority of sequences are gibberish/non-compiling code
• similarly, most random sequences of amino acids are lab-proven (Doug Axe’s work) to be non-functional gibberish
• the research showing this was conducted at Cambridge University and published in the Journal of Molecular Biology
• so, random mutation cannot explain the origin of the first living cell
• however, even natural selection coupled with random mutation cannot explain the first living cell
• there must already be replication in order for mutation and selection to work, so they can’t explain the first replicator
• but the origin of life is the origin of the first replicator – there is no replication prior to the first replicator
• the information in the first replicator cannot be explained by law, such as by chemical bonding affinities
• the amino acids are attached like magnetic letters on a refrigerator
• the magnetic force sticks the letters ON the fridge, but they don’t determine the specific sequence of the letters
• if laws did determine the sequence of letters, then the sequences would be repetitive
• the three materialist explanations – chance alone, chance and law, law alone – are not adequate to explain the effect
• the best explanation is that an intelligent cause is responsible for the biological explanation in the first replicator
• we know that intelligent causes can produce functional sequences of information, e.g. – English, Java code
• the structure and design of DNA matches up nicely with the design patterns used by software engineers (like WK!)

There are some very good tips in this lecture so that you will be able to explain intelligent design to others in simple ways, using everyday household items and children’s toys to symbolize the amino acids, proteins, sugar phosphate backbones, etc.

Proteins are constructed from a sequence of amino acids:

A sequence of amino acids forming a protein

Proteins sticking onto the double helix structure of DNA:

Some proteins sticking onto the sugar phosphate backbone

I highly, highly recommend this lecture. You will be delighted and you will learn something.

Here is an article that gives a general overview of how intelligent design challenges. If you want to read something more detailed about the material that he is covering in the lecture above related to the origin of life, there is a pretty good article here.

Related posts

• The kalam cosmological argument and the Big Bang theory
• The fine-tuning argument from cosmological constants and quantities
• The origin of life, part 1 of 2: the building blocks of life
• The origin of life, part 2 of 2: biological information
• The sudden origin of phyla in the Cambrian explosion
• Galactic habitable zones and circumstellar habitable zones
• Irreducible complexity in molecular machines
• The creative limits of natural selection and random mutation

Filed under: Videos, Amino Acid, Assembly, Bonding, Cell, Chance, Darwinism, Design Patterns, DNA, Doug Axe, Evidence, Evolution, Faith, Gene, Information, Intelligent Design, Law, Life, Materialism, Message, Messenger RNA, Naturalism, Necessity, OOL, Origin, Polymerase, Protein, Protein Folding, Protein Synthesis, Replicator, Ribosome, RNA, Science, Self-Organization, Sequence, Side Chains, Software Engineering, Specificity, Specified Complexity, Stephen C. Meyer, The DNA Enigma, William Dembski

New study: formation of life-permitting elements carbon and oxygen is fine-tuned

First, let’s review the structure of the fine-tuning argument.

The argument goes like this:

1. The fine-tuning of the universe to support life is either due to law, chance or design
2. It is not due to law or chance
3. Therefore, the fine-tuning is due to design

Here are the facts on the fine-tuning:

• Life has certain minimal requirements; long-term stable source of energy, a large number of different chemical elements, an element that can serve as a hub for joining together other elements into compounds, a universal solvent, etc.
• In order to meet these minimal requirements, the physical constants, (such as the gravitational constant), and the ratios between physical constants, need to be withing a narrow range of values in order to support the minimal requirements for life of any kind.
• Slight changes to any of the physical constants, or to the ratios between the constants, will result in a universe inhospitable to life.
• The range of possible values spans 70 orders of magnitude.
• The constants are selected by whoever creates the universe. They are not determined by physical laws. And the extreme probabilities involved required put the fine-tuning beyond the reach of chance.
• Although each individual selection of constants and ratios is as unlikely as any other selection, the vast majority of these possibilities do not support the minimal requirements of life of any kind. (In the same way as any hand of 5 cards that is dealt is as likely as any other, but you are overwhelmingly likely NOT to get a royal flush. In our case, a royal flush is a life-permitting universe).

Carbon is that element that can serve as a hub, and oxygen is also a vital element, since it is a component of water, which is required for life. So both carbon (the hub of large molecules) and oxygen (a building block of water) are required for complex life of any imaginable kind.

Now for the new study.

Reader Jen who blogs at Victory Rolls and V8s sent me this amazing article on Science Daily about a new peer-reviewed study that supports the fine-tuning argument.

Here’s an excerpt:

Life as we know it is based upon the elements of carbon and oxygen. Now a team of physicists, including one from North Carolina State University, is looking at the conditions necessary to the formation of those two elements in the universe. They’ve found that when it comes to supporting life, the universe leaves very little margin for error.

Both carbon and oxygen are produced when helium burns inside of giant red stars. Carbon-12, an essential element we’re all made of, can only form when three alpha particles, or helium-4 nuclei, combine in a very specific way. The key to formation is an excited state of carbon-12 known as the Hoyle state, and it has a very specific energy — measured at 379 keV (or 379,000 electron volts) above the energy of three alpha particles. Oxygen is produced by the combination of another alpha particle and carbon.

NC State physicist Dean Lee and German colleagues Evgeny Epelbaum, Hermann Krebs, Timo Laehde and Ulf-G. Meissner had previously confirmed the existence and structure of the Hoyle state with a numerical lattice that allowed the researchers to simulate how protons and neutrons interact. These protons and neutrons are made up of elementary particles called quarks. The light quark mass is one of the fundamental parameters of nature, and this mass affects particles’ energies.

In new lattice calculations done at the Juelich Supercomputer Centre the physicists found that just a slight variation in the light quark mass will change the energy of the Hoyle state, and this in turn would affect the production of carbon and oxygen in such a way that life as we know it wouldn’t exist.

[...]The researchers’ findings appear in Physical Review Letters.

So that’s the latest research that supports the fine-tuning argument. But how effective is this argument really? Is it only admitted by theists, or do atheists accept the fine-tuning as well?

Is the fine-tuning real?

Yes, it’s real and it is conceded by the top-rank of atheist physicists. Let me give you a citation from the best one of all, Martin Rees. Martin Rees is an atheist and a qualified astronomer. He wrote a book called “Just Six Numbers: The Deep Forces That Shape The Universe”, (Basic Books: 2001). In it, he discusses 6 numbers that need to be fine-tuned in order to have a life-permitting universe.

Rees writes here:

These six numbers constitute a ‘recipe’ for a universe. Moreover, the outcome is sensitive to their values: if any one of them were to be ‘untuned’, there would be no stars and no life. Is this tuning just a brute fact, a coincidence? Or is it the providence of a benign Creator?

There are some atheists who deny the fine-tuning, but these atheists are in firm opposition to the progress of science. The more science has progressed, the more constants, ratios and quantities we have discovered that need to be fine-tuned. Science is going in a theistic direction. Next, let’s see how atheists try to account for the fine-tuning, on atheism.

Atheistic responses to the fine-tuning argument

There are two common responses among atheists to this argument.

The first is to speculate that there are actually an infinite number of other universes that are not fine-tuned, (i.e. – the gambler’s fallacy). All these other universes don’t support life. We just happen to be in the one universe is fine-tuned for life. The problem is that there is no way of directly observing these other universes and no independent evidence that they exist.

Here is an excerpt from an article in Discover magazine, (which is hostile to theism and Christianity).

Short of invoking a benevolent creator, many physicists see only one possible explanation: Our universe may be but one of perhaps infinitely many universes in an inconceivably vast multiverse. Most of those universes are barren, but some, like ours, have conditions suitable for life.

The idea is controversial. Critics say it doesn’t even qualify as a scientific theory because the existence of other universes cannot be proved or disproved. Advocates argue that, like it or not, the multiverse may well be the only viable non­religious explanation for what is often called the “fine-tuning problem”—the baffling observation that the laws of the universe seem custom-tailored to favor the emergence of life.

The second response by atheists is that the human observers that exist today, 14 billion years after the universe was created out of nothing, actually caused the fine-tuning. This solution would mean that although humans did not exist at the time the of the big bang, they are going to be able to reach back in time at some point in the future and manually fine-tune the universe.

Here is an excerpt from and article in the New Scientist, (which is hostile to theism and Christianity).

…maybe we should approach cosmic fine-tuning not as a problem but as a clue. Perhaps it is evidence that we somehow endow the universe with certain features by the mere act of observation… observers are creating the universe and its entire history right now. If we in some sense create the universe, it is not surprising that the universe is well suited to us.

So, there are two choices for atheists. Either an infinite number of unobservable universes that are not fine-tuned, or humans go back in time at some future point and fine-tune the beginning of the universe, billions of years in the past.

Why the fine-tuning argument matters

We need to make a decision today about how we are going to live. The evidence available today supports the fine-tuning of the universe by a supernatural mind with immense power. The progress of science has strengthened this theory against determined opposition from rival naturalistic theories.

Those are the facts, and we must all choose what to do with them.

Further study

Here is a paper by Walter L. Bradley that contains many more examples of the fine-tuning, and explanations for what happens when you change the constants, quantities and rations even slightly.

Filed under: Polemics, Aliens, Amino Acid, Apologetics, Atheism, Carbon, Carbon-based Life, Chance, Complex Life, Constants, Cosmological Constants, Cosmology, Design, Fine Tuning, Habitability, Intelligent Design, Life, Liquid Water, Oxygen, Physical Laws, Physics, Probability Theory, Progress of Science, Protein, Solvent, Universal Solvent, Water